名称
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IKKγ NBD Inhibitory Peptide
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别名
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IKKγ NBD Inhibitory Peptide
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序列(单字母缩写)
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DRQIKIWFQNRRMKWKKTALDWSWLQTE
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序列(三字母缩写)
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{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}{Leu}{Gln}{Thr}{Glu}
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基本描述
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A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
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分子量
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3693.300
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化学式
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C170H259N49O42S1
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纯度
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> 95%
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存储条件
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Stored at -20°C. Keep tightly closed.
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注释
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