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服务
产品  
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Gly-Arg-Gly-Asp-Asn-Pro
| 名称
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Gly-Arg-Gly-Asp-Asn-Pro
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| 别名
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GRGDNP; GLY-ARG-GLY-ASP-ASN-PRO
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| 序列（单字母缩写）
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GRGDNP
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| 序列（三字母缩写）
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{GLY}{ARG}{GLY}{ASP}{ASN}{PRO}
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| 基本描述
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G-R-G-D-N-P is a superior inhibitor of cell attachment to fibronectin and a weak inhibitor of cell attacment to vitronectin. It also inhibits binding of fibrinogen, fibronectin, vitronectin and von Willebrand factor to platelets and resists to carboxypeptidases. G-R-G-D-N-P induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. It contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. G-R-G-D-N-P inhibits cell adhesion to fibronectin 80-90% at 1 mM.
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| 分子量
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614.600
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| 化学式
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C23H38N10O10
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Figures
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| Reference
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Sarin V, et al. Arginine-glycine-aspartic acid (RGD)-containing peptides inhibit the force production of mouse papillary muscle bundles via alpha 5 beta 1 integrin. J. Physiol. Apr 2005; 564(Pt 2): 603-617.
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