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产品  
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Glucagon (1-29), Human, Hydrochloride Salt
| 名称
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Glucagon (1-29), Human, Hydrochloride Salt
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| 别名
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Glucagon (1-29), Human
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| 序列（单字母缩写）
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HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
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| 序列（三字母缩写）
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{HIS}{SER}{GLN}{GLY}{THR}{PHE}{THR}{SER}{ASP}{TYR}{SER}{LYS}{TYR}{LEU}{ASP}{SER}{ARG}{ARG}{ALA}{GLN}{ASP}{PHE}{VAL}{GLN}{TRP}{LEU}{MET}{ASN}{THR}
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| 基本描述
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Glucagon is a single-chain polypeptide that contains 29 amino acid residues and has a molecular weight of 3,483. Glucagon is a hormone produced in the pancreas and it is used to raise very low blood sugar. Glucagon is also used in diagnostic testing of the stomach and other digestive organs. Glucagon increases blood glucose concentration and is used in the treatment of hypoglycemia. Glucagon acts only on liver glycogen, converting it to glucose. Glucagon administered through a parenteral route relaxes smooth muscle of the stomach, duodenum, small bowel, and colon.
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| 溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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3482.800
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| 化学式
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C153H225N43O49S1
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Reference
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Lee S, et al. PEGylated glucagon-like peptide-1 displays preserved effects on insulin release in isolated pancreatic islets and improved biological activity in db/db mice. Diabetologia. Jul 2006; 49(7): 1608-1611.
Aromataris EC, et al. Glucagon activates Ca2+ and Cl- channels in rat hepatocytes. J. Physiol. Jul 2006; 573: 611-625.
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