| 名称
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Fibrinogen Binding Inhibitor Peptide
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| 别名
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Fibrinogen Binding Inhibitor
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| 序列（单字母缩写）
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HHLGGAKQAGDV
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| 序列（三字母缩写）
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{HIS}{HIS}{LEU}{GLY}{GLY}{ALA}{LYS}{GLN}{ALA}{GLY}{ASP}{VAL}
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| 基本描述
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Fibrinogen Binding Inhibitor Peptide, a synthetic dodecapeptide, represents the specific platelet receptor recognition site of the human fibrinogen g-chain (residues 400-411). It is also a potent inhibitor of the binding of fibrinogen, fibronectin, and von Willebrand factor to thrombin- or ADP-stimulated platelets. Fibrinogen Binding Inhibitor Peptide has been used in studying phosphorylation processes associated with platelet activation.
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| 溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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1189.300
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| 化学式
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C50H80N18O16
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| 纯度
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> 95%
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| 存储条件
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Before using, store the peptide in the DRY form at 0-5°C. For and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
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| 注释
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In activated platelets, single γ 400-411 sequence is no longer required for initiation of adhesion but becomes sufficient for firm adhesion. In contrast to the binding of whole fibrinogen, binding of fragment 400-411 does not lead to tyrosine phosphorylation for platelet proteins.
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| Documents
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| Figures
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| Reference
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Fibrinogen Binding Inhibitor Peptide
