强耀生物科技
强耀生物
强耀生物
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强耀生物科技 Dermorphin
名称 Dermorphin
别名
序列(单字母缩写) YAFGYPS-NH2
序列(三字母缩写) {TYR}{d-ALA}{PHE}{GLY}{TYR}{PRO}{SER}-NH2
C-端 NH2
基本描述 Dermorphin has no common structure with mammalian opioid peptides. This peptide, isolated from the skin of the South American frog Phyllomedusa sauvagei, is the more selective of all m-opioid agonists.
溶解度 The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
分子量 802.900
化学式 C40H50N8O10
纯度 > 95%
存储条件 Storage at -20°C. Keep tightly closed.
注释
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Reference Ott D, et al. Engineering and functional immobilization of opioid receptors. Protein Eng. Des. Sel. Mar 2005; 18(3): 153-160. Mollereau C, et al. Neuropeptide FF (NPFF) analogs functionally antagonize opioid activities in NPFF2 receptor-transfected SH-SY5Y neuroblastoma cells. Mol. Pharmacol. Mar 2005; 67(3): 965-975. Xia WJ, et al. Partial neuroprotective effect of pretreatment with tanshinone IIA on neonatal hypoxia-ischemia brain damage. Pediatr Res. Oct 2005; 58(4): 784-790. Guan F., et al. Detection, quantification, and identification of dermorphin in equine plasma and urine by LC-MS/MS for doping control. Anal Bioanal Chem. 2013 May;405(14):4707 - 17.


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