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C-Type Natriuretic Peptide (CNP) (1-22), Human
名称
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C-Type Natriuretic Peptide (CNP) (1-22), Human
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别名
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CNP (1-22), humanCNP
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序列(单字母缩写)
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GLSKGCFGLKLDRIGSMSGLGC
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序列(三字母缩写)
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{GLY}{LEU}{SER}{LYS}{GLY}{CYS}{PHE}{GLY}{LEU}{LYS}{LEU}{ASP}{ARG}{ILE}{GLY}{SER}{MET}{SER}{GLY}{LEU}{GLY}{CYS}
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化学桥
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Disulfide bridge: Cys6-Cys22
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基本描述
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C-type natriuretic peptide is produced in the hypothalamus, anterior pituitary, and more major endocrine glands. C-type natriuretic peptide has potent venodilatory and coronary vasodilatory effects, but minimal effects on renal function.
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溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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分子量
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2197.600
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化学式
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C93H157N27O28S3
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纯度
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> 95%
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存储条件
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Store at -20°C.
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注释
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Pharmacological spectrum similar to ANP and BNP.
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Documents
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Figures
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Reference
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Anderson WG, et al. The effects of freshwater to seawater transfer on circulating levels of angiotensin II, C-type natriuretic peptide and arginine vasotocin in the euryhaline elasmobranch, Carcharhinus leucas. Gen. Comp. Endocrinol. May 2006; 147(1): 39-46.
Yeh LC, et al. C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation. J. Cell. Biochem. Feb 2006; 97(3): 494-500.
Hong TC, et al. Brain natriuretic peptide and C-type natriuretic peptide are differently regulated by age but similarly elevated in coronary artery disease. Acta. Cardiol. Feb 2006; 61(1): 1-5.
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