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产品
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CLIP (86-100)
名称
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CLIP (86-100)
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别名
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序列(单字母缩写)
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PVSKMRMATPLLMQA
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序列(三字母缩写)
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{Pro}{Val}{Ser}{Lys}{Met}{Arg}{Met}{Ala}{Thr}{Pro}{Leu}{Leu}{Met}{Gln}{Ala}
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基本描述
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This is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. This is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class II.
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分子量
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1674.100
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化学式
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C72H128N20O19S3
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纯度
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> 95%
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Documents
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Figures
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Reference
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Chen S., et al. Structure-Based Design of Altered MHC Class II–Restricted Peptide Ligands with Heterogeneous Immunogenicity. J Immunol. 2013 Nov;191(10):5097-106.
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