名称
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Calcitonin, Eel
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别名
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序列(单字母缩写)
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CSNLSTCVLGKLSQELHKLQTYPRTDVGAGTP-NH2
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序列(三字母缩写)
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{CYS}{SER}{ASN}{LEU}{SER}{THR}{CYS}{VAL}{LEU}{GLY}{LYS}{LEU}{SER}{GLN}{GLU}{LEU}{HIS}{LYS}{LEU}{GLN}{THR}{TYR}{PRO}{ARG}{THR}{ASP}{VAL}{GLY}{ALA}{GLY}{THR}{PRO}-NH2
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C-端
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NH2
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化学桥
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Disulfide bridge: Cys1-Cys7
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基本描述
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Calcitonin is hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Calcitonin decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.
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分子量
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3414.900
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化学式
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C146H241N43O47S2
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纯度
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> 95%
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存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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注释
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Calcitonin is A 32 amino acid polypeptide, 8 of which are conserved across all species.
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Documents
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Figures
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Reference
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Supowit SC, et al. Calcitonin gene-related peptide protects against hypertension-induced heart and kidney damage. Hypertension. Jan 2005; 45(1): 109-114.
Bowers MC, et al. Role of calcitonin gene-related peptide in hypertension-induced renal damage. Hypertension. Jul 2005; 46(1): 51-57.
Barbet J, et al. Prognostic impact of serum calcitonin and carcinoembryonic antigen doubling-times in patients with medullary thyroid carcinoma. J. Clin. Endocrinol. Metab. Nov 2005; 90(11): 6077-6084.
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