强耀生物科技
强耀生物
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强耀生物科技 Angiotensin I, Human
名称 Angiotensin I, Human
别名 Hypertensin IAngiotensin I human acetate hydrate; renin angiotensin; angiotensin receptor
序列(单字母缩写) DRVYIHPFHL
序列(三字母缩写) {ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{PRO}{PHE}{HIS}{LEU}
基本描述 Angiotensin I is a putative neurotransmitter. Angiotensin I is the precursor of angiotensin II and of angiotensin fragment 1-7, which are the hormones involved in regulation of fluid volume and the release of aldosterone.
溶解度 The peptide is soluble in water (10 mg/ml), clear, and colorless.
分子量 1296.480
化学式 C62H89N17O14
纯度 > 95%
存储条件 Store the peptide at -20°C. Keep container tightly closed.
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Reference Stanisavljevic S, et al. Angiotensin I-converting enzyme inhibitors block protein kinase C epsilon by activating bradykinin B1 receptors in human endothelial cells. J. Pharmacol. Exp. Ther. Mar 2006; 316(3): 1153-1158. Corradi HR, et al. Crystal Structure of the N Domain of Human Somatic Angiotensin I-converting Enzyme Provides a Structural Basis for Domain-specific Inhibitor Design. J. Mol. Biol. Mar 2006; 357(3): 964-974. Nikolaeva MA, et al. Testicular isoform of angiotensin I-converting enzyme (ACE, CD143) on the surface of human spermatozoa: revelation and quantification using monoclonal antibodies. Am. J. Reprod. Immunol. Jan 2006; 55(1): 54-68. Ahmad S., et al. Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue. PLoS One. 2011 Dec;6(12):e28501. Ahmad S., et al. Uptake and metabolism of the novel peptide angiotensin-(1-12) by neonatal cardiac myocytes. PLoS One. 2011 Jan;6(1):e15759.


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