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产品  
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Amylin, Amide, Rat
| 名称
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Amylin, Amide, Rat
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| 别名
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| 序列（单字母缩写）
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KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2
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| 序列（三字母缩写）
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{LYS}{CYS}{ASN}{THR}{ALA}{THR}{CYS}{ALA}{THR}{GLN}{ARG}{LEU}{ALA}{ASN}{PHE}{LEU}{VAL}{ARG}{SER}{SER}{ASN}{ASN}{LEU}{GLY}{PRO}{VAL}{LEU}{PRO}{PRO}{THR}{ASN}{VAL}{GLY}{SER}{ASN}{THR}{TYR}
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| C-端
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NH2
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| 化学桥
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Disulfide bridge: Cys2-Cys7
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| 基本描述
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Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a concentration-dependent decrease in acid secretion. In rat fundic segments, amylin and CGRP each caused a concentration-dependent increase in somatostatin and a decrease in histamine secretion.
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| 溶解度
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Can be dissolved in water directly
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| 分子量
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3920.500
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| 化学式
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C167H272N52O53S2
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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| Documents
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| Figures
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| Reference
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Stadler M, et al. Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function? Diabetes Care. May 2006; 29(5): 1031-1038.
Kairamkonda V, et al. Amylin peptide levels are raised in infants of diabetic mothers. Arch. Dis. Child. Dec 2005; 90(12): 1279-1282.
Takenaka S., etc. Organic Solvent-Tolerant Elastase Efficiently Hydrolyzes Insoluble, Cross-Linked, Protein Fiber Of Eggshell Membranes. Biotechnol Lett. 2012 May;34(5):949-55.
Guerreiro LH., etc. Amylin induces hypoglycemia in mice. An Acad Bras Cienc. 2013 Mar;85(1):349-354.
Guerreiro LH., etc. Preparation and Characterization of PEGylated Amylin. AAPS PharmSciTech. 2013 Sep;14(3):1083-1097.
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