服务
产品
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A-779
名称
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A-779
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别名
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序列(单字母缩写)
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DRVYIH{D-Ala}
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序列(三字母缩写)
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{ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{d-ALA}
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基本描述
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A-779 is a potent and selective Ang (1-7) antagonist. A-779 antagonizes several actions of Ang (1-7), including A-779's antidiurectic effect and the changes in MAP produced by Ang (1-7) microinjection into the dorsomedial or ventrolateral medulla.
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分子量
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873.000
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化学式
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C39H60N12O11
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纯度
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> 95%
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存储条件
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Store at -20°C.
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注释
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Documents
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Figures
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Reference
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Santos RA, et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension. May 2006; 47(5): 996-1002.
Iwata M, et al. Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects. Am J Physiol Heart Circ Physiol. Dec 2005; 289(6): H2356-H2363.
Gonzalez-Villalobos R, et al. Megalin binds and internalizes angiotensin-(1-7). Am J Physiol Renal Physiol. May 2006; 290(5): F1270-F1275.
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