服务
产品
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Rabbit Anti-Angiotensin II Antibody/血管紧张素Ⅱ抗体
名称
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Rabbit Anti-Angiotensin II Antibody
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中文名
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血管紧张素Ⅱ抗体
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基本描述
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AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
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抗体类型
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兔多抗
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免疫原
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偶联多肽或重组蛋白
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浓度
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1mg/ml
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存储条件
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Store at -20°C.
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亚型
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IgG
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成分
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亲和纯化,0.01M PBS(pH7.4),1% BSA
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应用
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IH(P)免疫组化(石蜡、冰冻);IC细胞免疫化学;WB免疫印迹等
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