|
服务
产品  
|
Rabbit Anti-APOJ Antibody/载脂蛋白J抗体
| 名称
|
Rabbit Anti-APOJ Antibody
|
| 中文名
|
载脂蛋白J抗体
|
| 基本描述
|
Apolipoprotein J is the major secreted product of Sertoli cells and is thought to play a critical role in spermatogenesis. The protein was shown to be a normal constituent of human blood and is also thought to be a control mechanism of the complement cascade. It prevents the binding of a C5b-C7 complex to the membrane of the target cell and in this way inhibits complement-mediated cytolysis.
Apolipoprotein J is overexpressed in human prostate and breast cancers and in squamous cell carcinomas. Suppression of Apolipoprotein J renders these cells sensitive to chemotherapeutic drug-mediated apoptosis. It has been proposed that elevated levels of Apolipoprotein J may promote oncogenic transformation and tumor progression by interfering with BAX proapoptotic activities.
|
| 抗体类型
|
兔多抗
|
| 免疫原
|
偶联多肽或重组蛋白
|
| 浓度
|
1mg/ml
|
| 存储条件
|
Store at -20°C.
|
| 亚型
|
IgG
|
| 成分
|
亲和纯化，0.01M PBS(pH7.4)，1% BSA
|
| 应用
|
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
|
|
