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服务
产品  
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Rabbit Anti-Angiotensin II type 1A receptor Antibody/血管紧张素Ⅱ1A型受体抗体
| 名称
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Rabbit Anti-Angiotensin II type 1A receptor Antibody
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| 中文名
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血管紧张素Ⅱ1A型受体抗体
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| 基本描述
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The Angiotensin II type 1 receptor (AT1) is the primary effector of Angiotensin II, a key regulator of blood pressure and fluid homeostasis. It is involved in pathogenesis of several cardiovascular diseases such as hypertension, cardiac hypertrophy and congestive heart failure. Angiotensin II interacts with two types of G-protein coupled membrane receptors, AT1 (type 1) and AT2 (type 2). AT1 has three isoforms in rodents: AT1A (359 aa), AT1B (359 aa), and AT1C (177 aa). Rat AT1's are predicted to contain seven transmembrane domains. The N-terminus is predicted to be extracellular, while the C-terminus is predicted to be cytoplasmic. AT1's are expressed in the liver, kidney, aorta, lung, uterus, ovary, spleen, heart, adrenal and vascular smooth muscle.
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| 抗体类型
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兔多抗
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| 免疫原
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偶联多肽或重组蛋白
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| 浓度
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1mg/ml
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| 存储条件
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Store at -20°C.
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| 亚型
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IgG
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| 成分
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亲和纯化，0.01M PBS(pH7.4)，1% BSA
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| 应用
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WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
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