服务
产品
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Rabbit Anti-AMPK beta 2 Antibody/腺苷单磷酸活化蛋白激酶β2抗体
名称
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Rabbit Anti-AMPK beta 2 Antibody
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中文名
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腺苷单磷酸活化蛋白激酶β2抗体
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基本描述
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PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.
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抗体类型
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兔多抗
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免疫原
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偶联多肽或重组蛋白
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浓度
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1mg/ml
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存储条件
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Store at -20°C.
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亚型
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IgG
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成分
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亲和纯化,0.01M PBS(pH7.4),1% BSA
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应用
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WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
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