服务
产品
|
Rabbit Anti-ARHGAP24 Antibody/Rho GTP酶激活蛋白24抗体
名称
|
Rabbit Anti-ARHGAP24 Antibody
|
中文名
|
Rho GTP酶激活蛋白24抗体
|
基本描述
|
ARHGAP24 is a rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. It acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. It controls actin remodeling by inactivating Rac downstream of Rho to suppress edge protrusion and promotes cell retraction to achieve cellular polarity. There are five different isoforms.Isoform 1 is widely expressed with a er level in kidney. Isoform 2 is mainly expressed in endothelial cells and is involved in modulation of angiogenesis.
|
抗体类型
|
兔多抗
|
免疫原
|
偶联多肽或重组蛋白
|
浓度
|
1mg/ml
|
存储条件
|
Store at -20°C.
|
亚型
|
IgG
|
成分
|
亲和纯化,0.01M PBS(pH7.4),1% BSA
|
应用
|
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500
IF=1:100-500
optimal dilutions/concentrations should be determined by the end user.
|
|