服务
产品
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Rabbit Anti-BDNF Antibody/脑源神经营养因子多抗体
名称
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Rabbit Anti-BDNF Antibody
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中文名
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脑源神经营养因子多抗体
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基本描述
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Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and to a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family.
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性 状
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Lyophilized or Liquid
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纯化方法
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affinity purified by Protein A or Protein G
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储 存 液
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0.01M PBS(pH7.4) with 1% BSA。
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存储条件
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Store at -20°C.
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