|
服务
产品  
|
Human TNF-alpha / TNFA Protein/重组人 TNF-alpha / TNFA 蛋白
| 名称
|
Human TNF-alpha / TNFA Protein/重组人 TNF-alpha / TNFA 蛋白
|
| 中文名
|
Human TNF-alpha / TNFA Protein/重组人 TNF-alpha / TNFA 蛋白
|
| 基本描述
|
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.
|
| 分子别称
|
TNF-alpha, TNF-a, Cachectin, DIF, TNFA, TNFSF2
|
| 分子种属
|
Mouse
|
| 表达标签
|
His，S
|
| 表达宿主
|
E. coli
|
| 纯度
|
> 95 % as determined by SDS-PAGE
|
| 缓冲液
|
Lyophilized from sterile PBS, pH 7.4
|
| 保存方法
|
-70°C，应避免反复冻融。
|
|
