| 名称
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[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human
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| 编码
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| 别名
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[Lys(Ac)373]-p53 (368-393), p53 K373(Ac), biotin-labeled, human
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| 纯度
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80%，90%，95%，98%，99%
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| 重量
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1mg,5mg,10mg,50mg,100mg,1g
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| 序列（单字母缩写）
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Biotin-KGGHLKSK-K(Ac)-GQSTSRHKKLMFKTEGPDSD-NH2
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| 序列（三字母缩写）
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Biotin-Lys-Gly-Gly-His-Leu-Lys-Ser-Lys-Lys(Ac)-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2(trifluoroacetate salt)
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| 基本描述
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This is a biotin-labeled and amidated peptide derived from residues 368-393 of human p53 tumor suppressor protein with acetylation at Lys373 and additional KGW residues on its N-terminus. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo.
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| 溶解度
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| 分子量
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3481
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| 化学式
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Figures
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| Reference
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Kanovsky, M. et al. Proc Natl Acad Sci 98, 12438 (2001)
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| C端
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| N端
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| 化学桥
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