| Name
|
Vasoactive Intestinal Contractor [VIC]
|
| Code
|
|
| The alias
|
Vasoactive Intestinal Contractor [VIC]
|
| Sequence (single letter abbreviation)
|
CSCNSWLDKECVYFCHLDIIW (C1&C15 bridge, C3&C11 bridge)
|
| Sequence (three-letter abbreviation)
|
H-Cys-Ser-Cys-Asn-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (trifluoroacetate salt)(Cys1 and 15 bridge, Cys3 and 11 bridge)
|
| A basic description
|
Potent vasoconstrictor that acts on endothelia cells and on the underlying smooth muscle cells as a modulator of vascular tone. ET-1 displays selectivity for ETA receptor.
|
| solubility
|
|
| The molecular weight
|
2574
|
| Chemical formula
|
C116H161N27O32S4
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
N. Ishida et al., FEBS Letters, 247, 337 (1989)
K. Saida et al., J. Biol. Chem., 264, 14613 (1989)
M.S. Simonson et al., FASEB J., 4, 2989 (1990)
|
| The C-terminal
|
|
| The N-terminal
|
|
| Chemical bridge
|
(Cys1 and 15 bridge, Cys3 and 11 bridge)
|