| Name
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Chromozym-tPA
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| Code
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| The alias
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Chromozym-tPA
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| Sequence (single letter abbreviation)
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N-Methylsulfonyl-DPhe-GR-pNA
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| Sequence (three-letter abbreviation)
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N-Methylsulfonyl-DPhe-Gly-Arg-pNA (trifluoroacetate salt)
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| A basic description
|
ACE FRET substrate I that is derived from the cleavage sequence of pro-TNFa recognized by the TNFa-cleaving enzyme (TACE). TNFa is presumably shed from cell membranes by TNFa-cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-convertase.
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| solubility
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|
| The molecular weight
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576.5
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| Chemical formula
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C24H32N8O7S1
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| The purity
|
80%，90%，95%，98%，99%
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| Weight
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1mg,5mg,10mg,50mg,100mg,1g
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| Storage conditions
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| Annotation
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| Documents
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| Figures
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| Reference
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| The C-terminal
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| The N-terminal
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| Chemical bridge
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