| Name
|
Thrombin Substrate III, Fluorogenic
|
| Code
|
|
| The alias
|
Thrombin Substrate III, Fluorogenic
|
| Sequence (single letter abbreviation)
|
Benzoyl-FVR-AMC
|
| Sequence (three-letter abbreviation)
|
Benzoyl-Phe-Val-Arg-AMC (trifluoroacetate salt)
|
| A basic description
|
A stromelysin-1 substrate, which is also hydrolyzed by two other matrix metalloproteinases, collagenase and gelatinase, and by the bacterial metalloproteinase thermolysin. The thiopeptolide Ac-PLA-psi[COS]Nva-W-amide mimics the MMP-3 cleavage site Leu-Ala-Nva-Trp
|
| solubility
|
|
| The molecular weight
|
681.8
|
| Chemical formula
|
C37H43N7O6
|
| The purity
|
80%,90%,95%,98%,99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
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| Documents
|
|
| Figures
|
|
| Reference
|
L. Svendsen, et al., Folia Haematol, 98, 446 (1972)
R. Lottenberg, et al., Meth. Enz., 80, 341 (1981)
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| The C-terminal
|
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| The N-terminal
|
|
| Chemical bridge
|
|