| Name
|
Tamra-β-Amyloid (1-28)|Tamra-beta-Amyloid (1-28)
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| Code
|
[109770-29-8]
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| The alias
|
Tamra-β-Amyloid (1-28)|Tamra-beta-Amyloid (1-28)
|
| Sequence (single letter abbreviation)
|
Tamra-DAEFRHDSGYEVHHQKLVFFAEDVGSNK
|
| Sequence (three-letter abbreviation)
|
Tamra-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH (trifluoroacetate salt)
|
| A basic description
|
Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
|
| solubility
|
|
| The molecular weight
|
3676
|
| Chemical formula
|
C170H230N43O50
|
| The purity
|
80%,90%,95%,98%,99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
J. Kang et al., Nature, 325, 773 (1987)
|
| The C-terminal
|
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| The N-terminal
|
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| Chemical bridge
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