| Name
|
Dermaseptin
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| Code
|
|
| The alias
|
Dermaseptin
|
| Sequence (single letter abbreviation)
|
ALWKTMLKKLGTMALHAGKAALGAAADTISQGT
|
| Sequence (three-letter abbreviation)
|
Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln
|
| A basic description
|
Cysteine-rich cationic peptide with antiviral activity against HSV infection and a role in N. gonorrhoeae-mediated HIV enhancement. In contrast to the other members of the ?-defensin family it shows very low antimicrobial activity against Gram-negative and Gram-positive bacteria. As a biomarker of colon adenocarcinoma it may have utility in colon cancer screening and diagnosis.
|
| solubility
|
|
| The molecular weight
|
3455.1
|
| Chemical formula
|
C152H257N43O44S2
|
| The purity
|
80%，90%，95%，98%，99%
|
| Weight
|
1mg,5mg,10mg,50mg,100mg,1g
|
| Storage conditions
|
Store at -20°C. Keep tightly closed. Store in a cool dry place.
|
| Annotation
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
A. Mor et al., Biochemistry, 30, 8824 (1991)
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| The C-terminal
|
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| The N-terminal
|
|
| Chemical bridge
|
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