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产品  
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Β-Amyloid (1-16)
| 名称
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Β-Amyloid (1-16)
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| 别名
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| 序列（单字母缩写）
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DAEFRHDSGYEVHHQK
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| 序列（三字母缩写）
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{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}{Val}{His}{His}{Gln}{Lys}
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| 基本描述
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Proteins interactions with reactive oxygen agents may result in covalent modifications of amino acid residues in proteins, formation of protein-protein cross-linkages and oxidation of the protein backbone resulting in protein fragmentation. Oxidation targets for Beta-amyloid (1-16) are the histidine residues coordinated to the metal ions. Copper is bound to Aß in senile plaque of Alzheimer’s disease with Beta-amyloid (1-16) taking part in the coordination of the Cu2+ ions. Cu2+ and Zn2+ are linked with the neurotoxicity of Aß and free radical damage.
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| 分子量
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1955.020
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| 化学式
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C84H119N27O28
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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| Reference
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Please add reference: Da Silva, GFZ. et al. J. Biol. Chem. 280, 16601 (2005)
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