| 名称
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[Sar9]-Substance P
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| 别名
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rNK1-specific agonist
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| 序列(单字母缩写)
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| 序列(三字母缩写)
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{ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{SAR}{LEU}{MET}-NH2
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| C-端
|
NH2
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| 基本描述
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The neuropeptide substance P(SP) is a major mediator of neurogenic inflammation and immunomodulatory activities within the central and peripheral nervous system. [Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.
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| 溶解度
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Other solvents: Insoluble in ether & benzene.
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| 分子量
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1361.660
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| 化学式
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C64H100N18O13S
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Figures
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| Reference
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Patte-Mensah C, et al. Substance P inhibits progesterone conversion to neuroactive metabolites in spinal sensory circuit: a potential component of nociception. Proc. Natl. Acad. Sci. U.S.A. Jun 2005; 102(25): 9044-9049.
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