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服务
产品  
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PAR-1 Agonist Peptide
| 名称
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PAR-1 Agonist Peptide
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| 别名
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| 序列（单字母缩写）
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SFLLRN
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| 序列（三字母缩写）
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{Ser}{Phe}{Leu}{Leu}{Arg}{Asn}
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| 基本描述
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This hexapeptide corresponding to residues 42-47 of the thrombin receptor has been shown to be a thrombin receptor activator. It caused half-maximal platelet aggregation at approx. 0.8 uM and was 5 times more potent than the parent peptide H-8105. In addition, SFLLRN is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+.
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| 分子量
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748.870
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| 化学式
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C34H56N10O9
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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| Documents
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| Figures
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| Reference
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Simmons Sarah., et al. Thrombin induces release of proinflammatory chemokines interleukin-8 and interferon-c-induced protein-10 from cultured human fetal astrocytes. Neuroreport. 2013 Jan;24(1):36-40.
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