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服务
产品  
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Orexin B, Human
| 名称
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Orexin B, Human
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| 别名
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| 序列（单字母缩写）
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RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
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| 序列（三字母缩写）
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{ARG}{SER}{GLY}{PRO}{PRO}{GLY}{LEU}{GLN}{GLY}{ARG}{LEU}{GLN}{ARG}{LEU}{LEU}{GLN}{ALA}{SER}{GLY}{ASN}{HIS}{ALA}{ALA}{GLY}{ILE}{LEU}{THR}{MET}-NH2
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| C-端
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NH2
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| 基本描述
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Orexin B is a hypothalamatic neuropeptide stimulating food intake in rats. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons. Orexin B stimulates food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX1 receptor is significantly lower than that of orexin A. Binding affinities for the OX2 receptor are similar for orexin A and B.
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| 溶解度
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Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
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| 分子量
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2899.340
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| 化学式
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C123H212N44O35S1
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C.
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| 注释
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| Documents
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| Figures
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| Reference
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Haj-Dahmane S, Shen RY. The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling. J. Neurosci. Jan 2005; 25(4): 896-905.
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