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服务
产品  
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InsB 9-23
| 名称
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InsB 9-23
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| 别名
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| 序列（单字母缩写）
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SHLVEALYLVCGERG
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| 序列（三字母缩写）
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{Ser}{His}{Leu}{Val}{Glu}{Ala}{Leu}{Tyr}{Leu}{Val}{Cys}{Gly}{Glu}{Arg}{Gly}
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| 基本描述
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This insulin B-chain peptide binds to a class II histocompatibility complex (MHC) allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic ß cells to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
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| 分子量
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1645.900
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| 化学式
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C72H116N20O22S1
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| 纯度
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> 95%
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| 存储条件
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Stored at -20°C.
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| 注释
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| Documents
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| Figures
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| Reference
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Devendra D,Diabetes. 2005 Sep;54(9):2549-56.
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