| 名称
|
IKKγ NBD Inhibitory Peptide
|
| 别名
|
IKKγ NBD Inhibitory Peptide
|
| 序列(单字母缩写)
|
DRQIKIWFQNRRMKWKKTALDWSWLQTE
|
| 序列(三字母缩写)
|
{Asp}{Arg}{Gln}{Ile}{Lys}{Ile}{Trp}{Phe}{Gln}{Asn}{Arg}{Arg}{Met}{Lys}{Trp}{Lys}{Lys}{Thr}{Ala}{Leu}{Asp}{Trp}{Ser}{Trp}{Leu}{Gln}{Thr}{Glu}
|
| 基本描述
|
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.
|
| 分子量
|
3693.300
|
| 化学式
|
C170H259N49O42S1
|
| 纯度
|
> 95%
|
| 存储条件
|
Stored at -20°C. Keep tightly closed.
|
| 注释
|
|
| Documents
|
|
| Figures
|
|
| Reference
|
|