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服务
产品  
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Eptifibatide
| 名称
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Eptifibatide
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| 别名
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Integrilin
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| 序列（单字母缩写）
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| 序列（三字母缩写）
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MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2
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| C-端
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NH2
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| 化学桥
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Mpa1-Cys7
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| 基本描述
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Eptifibatide is a cyclic heptapeptide containing six amino acids and one mercaptopropionyl (des-amino cysteinyl) residue. An interchain disulfide bridge is formed between the cysteine amide and the mercaptopropionyl moieties. Chemically it is N6 -(aminoiminomethyl)-N2 -(3-mercapto-1-oxopropyl-L- lysylglycyl-L-a-aspartyl- L-tryptophyl-L -prolyl-L-cysteinamide, cyclic (1Ø6)-disulfide. Eptifibatide binds to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibits platelet aggregation
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| 分子量
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831.960
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| 化学式
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C35H19N11O9S2
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| 纯度
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> 95%
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| 存储条件
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Store at -20°C. Keep tightly closed. Store in a cool dry place.
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| 注释
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| Documents
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| Reference
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Coons JC, Barcelona RA et al. Eptifibatide-associated acute, profound thrombocytopenia. Ann Pharmacother. Feb 2005;39(2):368-72.
Gurbel PA, Bliden KP et al. Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study. Circulation. Mar 2005;111(9):1153-9
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